Bob Bailey takes the title role in this detective drama. As George Valentine he acquired his cases through the following newspaper advertisement: “Personal Notice – Danger’s my stock-in-trade. If the job’s too tough for you to handle, you've got a job for me, George Valentine. Write full details.” The George of this series is not, however, the thug one might imagine... He uses his scientific talents to crack the cases, although his character does evolve to some extent and by the end of the show’s run he is capable of taking on the best of them. The show also features the character Brooksie (played originally by Frances Robinson then later by Virginia Gregg and Lillian Buyeff) as George’s secretary who, in later episodes, sets her sights on the boss.